William Muirhead was born in 1802 in Niagara, Ontario. He settled in the Brantford area in 1825. On October 15th, 1830, William bought the first piece of Brantford Town Plot property sold through public auction. It was described as Lot 8 consisting of 21,000 square links on the North side of Colborne Street, on which he built a house known as "Oakwood.”
On September 6, 1847, the first Town Councillors were elected; one member for each of the seven wards. The first Brantford City Council meeting was held at "Bradley's Inn" on September 9, 1847 to elect a Mayor from the assembled Town Councillors. William Muirhead had the honour of being elected and thus became the first Mayor of the Town of Brantford in 1847.
He did not run for re-election in 1848 and was succeeded by Mayor Dr. Digby. The first bylaw to be signed by Mayor Muirhead was on September 15, 1847; Bylaw No. 1. It was introduced to prevent horses and swine from running at large anytime; and cattle from running at large between December 1 and May 1.
In the 1830's, William opened the Town's first Bank of Montreal branch. In that position he had a pivotal role in the financing of Brantford's first businesses and was reported to be "well remembered by the early businessmen" from that era. William died in 1882 and is buried in Greenwood Cemetery in Brantford.